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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f4e687a5910835166ee4b0fda0662161d93568164a4c2741b3e2841af72a4e8b' 
  AND token = 'MmR4oNwPFwC/i48Fo+IhHaOK8hXB6KbuJ57XmVYbb88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}