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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49fb413b6fa8a6922b07a530f4c6c2632958e609c40f347999a432bdc2c668db' 
  AND token = 'grK3V8kD6H+G5nWntT+Tovtx6ajmxy5fUcPlSoMCR6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}