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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7c3b104c97c19e22c2420f7e75ac42e1f821db46c47d17fc8b309bba79e9711c' 
  AND token = 'fb6oLtioEbCnG38MMoriwAe+UjGwupyOVfC447eM3oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}