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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cb2af2eb57bba85d9641851d841021291f7a3a8a26df4de91b690c51b5fca310' 
  AND token = '2K0E1TG6Ygn2r3WUJhK08Ig2YGy3S7VAS1vmLqbVLs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}