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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '217e86d77c910e816be87fbf81b453bc29bb540324345a62257a1d1e720933cb' 
  AND token = 'eo65xGC6FM1QQ99mAIvOLtWS4k3auYQrNogCwiOvFV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}