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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3b48753f8be8c992b7970fe1d1afa10fceed8253a7cb928d9c5ca58254037785' 
  AND token = '+cU86k44Vsd++CKeerGNRbtQ0/gQBKmIPSZpltW2NB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}