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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e038786fc6c9f6080227818092675c1f983658dbc084c5bb822ee4660f84c365' 
  AND token = '7pOJ3RTrq+q64RbSE8tMwQ0sSJ9x6uRfPtLFAny6DxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}