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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '281b7d4860c000b07a449e7693f306bb85ee5eb3732b31e295e4c24700eaaef1' 
  AND token = 'G1USMXCqCl3wRYOltCkIHAd0CfaLydu7+4ZcJImRWn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}