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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '42549b01dacc179ba3c6488c9801bb9cd21c2bd2c3cf80e115090765eadd8712' 
  AND token = 'egu6d1eLSNPfRMER7+VBt0csu9R0gZzpjTNzP+WRolM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}