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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b4ae2e2485a096984a47b65a0ae5dc4f8def0c57cdea7e6bbe36c39d4494a645' 
  AND token = '0brFz/GeHZBH2ZOvy6Xa3+I5oD9hDLrcMLw2TYjFqH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}