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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '156fa7cdffaef78e7d4c9574dacded5379bb50901c25d591a050f3d8bc37d052' 
  AND token = 'TJ1w3E4+NNz1js4vU6Dw4vGWUo4Gzr737X8Pm6daGm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}