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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e487f68d4634151282d306425218f59616edce5ab66dd8f270f7d9269234405' 
  AND token = 'EhHeqIySEvBNt6bFwpLzs+099j4X1tjsLQQDq7r0svM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}