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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b59121c5c50b32ca20aeee097d19851e4e1a4d70a6e72f65846f3513984fdc04' 
  AND token = '3iepLueKHDVS3Edxt/8gFmrVhFMOxuP8FtEzgEIWCyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}