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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2eaa7e246cacdca201f33788ec179ba9d2268cb56b546077ebb9c6f3eb68def4' 
  AND token = 'B8znDBfcoYwvp2NILK3rnTLk/0dKnpbwTREkv67lP5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}