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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '16e12b91e406be235f764836d396881ce1751ff3d75a54177865bbc4abcc38a8' 
  AND token = '281AWVItNfUqIIOLELAUQCb5ifoYIP1hxlu8BgIaZeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}