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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '06f21cbb6b4df6f5b4059349ff9fcf29d0043d63cdf59cb079d5553e9d84f900' 
  AND token = '+XGKxHkturZEM+q49bkXcpd0l7+bUNEB4lbsEyxGEj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}