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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65e0a6cad2017426d7cddf8a3f676f464f4537f7c86f3e292da84eff57fb96ee' 
  AND token = 'bJXcwCc7kLyhFk8oguOBCZ5lzzEkCs5bIp7u+CfvaHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}