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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2ff1890c54ca9219667cba8e0fc16eb44dc20227d7a82d12e230c8a4ff03a277' 
  AND token = '6ZNEAS49ZPa0++ihbUEb6EM3uTKAIPKFmvGARX9v3Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}