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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c422c1b03fe1984972f96c102aafbaa4d6025097a700e757ff9b8817cf710247' 
  AND token = 'aWyl+d5GaM6ksmgtF3/LyFcFoiiAWAcDlBqtNMs1iJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}