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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '88a9cdaac4dfe5b4c41c783db3686f1de1272dbf6021e9034e18684571db72de' 
  AND token = 'PGvWPI+HQGtVLjjkMtrAmtXYT0InlN46WC1gOXe37MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}