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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e86d17d5263937575c27934cd5266cdf706a227bf025ac2be1cb3bf989177d2' 
  AND token = 'XvD9HIVK59+63tS2f1nCc3utZkR/uIYcBT0Lr5pq2Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}