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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3821ebad7f8ea29cdb9e5b4c6d90978d58ac0a2c30582a4b4dca95ffea8f0091' 
  AND token = '/5urS/L27LPwOF8PJNwciHQf1BEIHrULYJ2RMgHI5xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}