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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8ff235b27be8c95a964359eadd0c55d279d8aa1eb5098eb75416b9781f797c1c' 
  AND token = 'HZ2MHncjPm32FsNm9SSHNWvOwDPfRVlbPr2Cn0fKnLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}