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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b4428e84efb949252774f133dfc9978e2c46399194ff703b0d877dd86d267283' 
  AND token = 'LRfstdDs9ySbxPL3uX/99PUNlWMZCHwfwn03OtOXhMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}