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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '108766ce080e099b284b1d24975d20a6aed195e14bc005e758d6054cafc4825f' 
  AND token = 'FCA8F47lYPE/x3kdtcYV2xqEUFmqpXS0/AlQ2ETQluA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}