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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1222d46d06f4babcb06612aa1431911d8cba4f2b9c5321f045174d4a95757946' 
  AND token = 'P59R0AsEVQuh3k2VO1mO9x8sg2H/+gIsUxO4Qell8mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}