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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e62c34f64a0b5bac75e7be5c8d299759f365d62588ec372331faa56eff4a6605' 
  AND token = 'GHX6p1TIDi5tWk627sqtGiPguOTQaMzZK+wG40pdzSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}