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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3cfce849388e32b4f57237769e758c165730726e67caf41c3309dada30452305' 
  AND token = 'h84bh3L69v+uPweAw8TeqazldkgCkPXnwrSU8f95Ub4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}