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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd23e6447be0018d2cc8f290c90f946f94a95400be31929fe1f7b660c35aae57b' 
  AND token = '+io26b5/vFp06Vg1PinWHk6a/tHKxyrmXDwpkYbRcb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}