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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'dfa1cfc1b83d6bdb4895bc192d0945f490a7d6afdf67fa70402505eeb1b3149b' 
  AND token = 'Nv3t/2mTNfmsNVnm4UbhMV6IZHnCmlewSAOMZgO2+rA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}