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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9dfc89818aba414e4c664878572e9c08576cfbc26de0c971702a2b693e9e8044' 
  AND token = 'DycLLcKLx77cJGHUPkUM9fP3x9daEcEcH/0pK8vH+m4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}