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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ec22628677be2b037b6dbbe78cee58e5c98208a771e1438893bcc963bf1fb199' 
  AND token = 'W7n1lLTCz1zh8D6LLQSLozPdfsIkD9ed4B0r9CGgp3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}