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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '449c72c0df686150b28bde8e506e2da7f701f1f3bc5b0c1155ac8b4303a3087f' 
  AND token = 'kXvHBxUQB7fCTpo0oZcJBC6wd66HIv0fOlkaoPk5qxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}