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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9dc50e4215e0de9dbff36f98160a0e8cca247ade525b2cc6a43e1195d568fecc' 
  AND token = 'snRhRQ5cXTRzGwPbBfA8jjMJ3RPSLcKsUCxAPmxs73A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}