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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5871d5e60b39e7611dd401afb0583b6418736dc74d72de8e617e56839d0fe52e' 
  AND token = 'wpqp9G+rO+bNDTA2qkN46PhdTRTJwtHdwiY+uMk5D/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}