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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8c50cbb1c8c2009b4e051a00e16f1329fb507b4db652d55db601f6b8841aace2' 
  AND token = 'oxzA2bZ8rgxGiKYD2sAlWZCmxABBASLBtsSwZL6NhOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}