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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '09709d063b3c541273ad084c7806e09941764d7880f6235d2446a0490d223be5' 
  AND token = 'j18iIjUyTH0bW/W3JkjIgxFNmzi2xSEqbTpz/jephkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}