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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ddc72f8fca739b99d7c59885c080b2a1d8ca103e5added7258f4bc38688e0e4d' 
  AND token = 'VA3oFYVw8nj+D0uT1sOWGBqctLWsYnMO+ScTB6WO4Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}