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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1ea879b095bc679e2045ca69ceed3443df7a2678c226b493b9e314e9b45bd759' 
  AND token = 'DO4XLyJHQmgBaQeyezTcDsyXmxFLg1M8XWiJ+5NncwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}