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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a6b05b89aa21e6acb98e00062549d59bfc21309cefa1734f8888ad7fe75a4b68' 
  AND token = 'HdB5Nd9p8XYVqZcVrFmyowvI5+I3MjoNkl8vCw2pro4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}