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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fa143e208fbd03de8caccc8c2a2d06382cc6420fd8b79e831d3d227a789dbf85' 
  AND token = '935zf5gIQ1kaUY/bCSuLFNbpRpFcNA3t7yNxdSJ5OmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}