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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7b22976088da52109b57d60fdde2a5d9f7cf37e8146bcee643887b3dede4bcb9' 
  AND token = 'IiWyAsxTtMYtkmpbfeoDAGm6FDa+X/5M8ylHK/I8t9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}