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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '397160581b70c8ad5fa959c2f334dd73d1db4fde8752a990a2cd621a77f5bbc5' 
  AND token = 'rdQSImQ42Qn/PgidQbDN7CT0aI13WjsGWwUKbhZyGdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}