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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fae576aa3672588802b3fc9c6326d6c3980df76df1ace3727f7cc60967d4d595' 
  AND token = '43igedWpxCNV7CEunzpwxWuHT32SMP3oD6+zviYPoD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}