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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46b7b083d4d6404ab3a4e4fce282c046eedf8dcf6e2b225a4d546a98245c5eb3' 
  AND token = 'KQgtbG7bZKIVMdzkSX1vGMPDAZRHOyzw6o38io+sDuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}