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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c389749cf777859bd01f22cd79cf0da955fba1e922a290843776a018a04e26a4' 
  AND token = 'B5rVB9AKJ0HoAYo4WroGn58mfgr/dDN5RNHVYS7cbH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}