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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c53e57dec0538a429cf9c643bb7776bdfe844d7112ba44df3f7763aac9421d91' 
  AND token = 'EEj7/vzNJ2n2b7vJcBgiEkLbmatNcwrcdru+MZEjvRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}