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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e252f40cb775bf48333656daacd73a95b65ec4203f413b78738df48daeffaed' 
  AND token = '61atVq98dy8//IuGVKD13I5l+6mVXen5ApqwQV5YHPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}