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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '64f2daee7c45d6e3eb7d6ddc83b235f3abc611b7085b466e75c06250bc6898b1' 
  AND token = 'P2atMUyezOTtgLltAhb0BTYIHMCNocodlDNV609OwEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}