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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '362e5a78bca1daaa2b1dc3137b789be3cb2ccd1c18d60e2111025debbfaeb00b' 
  AND token = 'C0w67KXOTsQh5IO6S4u7VKJhmnJ4zLKXry3YtEkJDio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}